Principal Research Scientist II, Process Chemistry (Radiochemistry)

$141K - $268K North Chicago, IL, US Senior Research Scientist

Interested in this Research Scientist role at AbbVie?

Apply Now →

About This Role

AI job market dashboard showing open roles by category

Company Description About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience \- and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

AbbVie Process Chemistry is responsible for the chemical development of AbbVie’s clinical candidates. We are seeking a Principal Research Scientist II to lead the Radiochemistry team that is responsible for labeling experimental drug candidates from preclinical through clinical development.

We are looking for a highly motivated person who can drive the development of drug candidates from early discovery to late\-stage development through radiolabeling. The candidate will lead a group of scientists in the labeling of materials with tritium and 14C. The candidate will serve as the primary contact for labeling requests and as such would be responsible for developing strategies, timelines, and key activities required for radiolabeled drug substances. The candidate must be able to mentor and develop staff with experimental approaches to solve difficult scientific and technical challenges. Working with discovery, drug metabolism, analytical and chemistry colleagues, the candidate will develop productive collaborations and effectively communicate with scientific teams.

Responsibilities:

  • The candidate will lead activities associated with labeling and characterization for new drug substances.

+ Lead the design and execution of labeling strategies.

+ Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management. Mentor staff in troubleshooting strategic and experimental issues.

+ Author and review key regulatory documents, laboratory data, technical memos, standard operating procedures, and reports.

+ Collaborate to ensure successful CMC interactions with regulatory authorities.

  • The position involves multi\-disciplinary interactions with organic chemists, analytical chemists, engineers, drug metabolism scientists, formulators, and program management. The candidate will utilize his/her expertise across disciplines to advance the pipeline.
  • The candidate will encourage ideas for continuous improvement activities and initiatives within the Radiochemistry team.
  • The candidate will understand, adhere, and ensure compliance with corporate standards regarding code of conduct, safety, radiosafety and GXP compliance.

Qualifications

  • BS (16\+ years); MS (14\+ years) or PhD (8\+ years) in Chemistry or allied field, with 8\+ years of previous work experience in a pharmaceutical laboratory setting.
  • Experience in radiolabeling and safety.
  • Experience in managing and developing scientific leaders is required.
  • The successful candidate will have a strong understanding of synthetic organic chemistry, process development, GXP compliant processes, and radiolabeling strategies to appropriately label compounds to meet the study needs.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our long\-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US \& Puerto Rico only \- to learn more, visit https://www.abbvie.com/join\-us/equal\-employment\-opportunity\-employer.html

US \& Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join\-us/reasonable\-accommodations.html

Salary Context

This $141K-$268K range is above the 75th percentile for Research Scientist roles in our dataset (median: $183K across 83 roles with salary data).

Role Details

Company AbbVie
Title Principal Research Scientist II, Process Chemistry (Radiochemistry)
Location North Chicago, IL, US
Category Research Scientist
Experience Senior
Salary $141K - $268K
Remote No

About This Role

Research Scientists push the boundaries of what AI can do. They design experiments, develop novel architectures, publish papers, and translate research breakthroughs into production capabilities. This is where the fundamental advances happen, from attention mechanisms to diffusion models to reasoning chains.

The work is intellectually demanding and often ambiguous. You might spend months on an approach that doesn't pan out. The best research scientists combine deep mathematical intuition with engineering pragmatism. They know when to go deep on theory and when to run experiments. They read papers voraciously and can spot incremental contributions from genuine breakthroughs.

Across the 3,708 AI roles we're tracking, Research Scientist positions make up 3% of the market. At AbbVie, this role fits into their broader AI and engineering organization.

Research Scientist roles are concentrated at major AI labs (OpenAI, Anthropic, Google DeepMind, Meta FAIR) and well-funded AI startups. The competition is intense. PhD is effectively required for most positions, and publication track record matters. Compensation is among the highest in AI, reflecting both the scarcity of talent and the strategic importance of research breakthroughs.

What the Work Looks Like

A typical week includes: reading and discussing recent papers with your team, designing and running experiments on multi-GPU clusters, analyzing results and iterating on hypotheses, writing up findings for internal review or publication, and collaborating with engineering teams to productionize promising results. The ratio of thinking to coding is higher than in engineering roles.

Research Scientist roles are concentrated at major AI labs (OpenAI, Anthropic, Google DeepMind, Meta FAIR) and well-funded AI startups. The competition is intense. PhD is effectively required for most positions, and publication track record matters. Compensation is among the highest in AI, reflecting both the scarcity of talent and the strategic importance of research breakthroughs.

Skills in Demand for This Role

Python (51% of roles) Aws (30% of roles) Azure (24% of roles) Rag (23% of roles) Gcp (17% of roles) Prompt Engineering (15% of roles) Pytorch (15% of roles) Claude (13% of roles)

PhD strongly preferred for most roles. Deep expertise in a specific area (NLP, computer vision, reinforcement learning, multimodal) is expected. PyTorch is the standard. Publication track record matters. Strong mathematical foundations in linear algebra, probability, optimization, and information theory are assumed.

Beyond the fundamentals, companies value experience with large-scale distributed training, novel architecture design, and the ability to bridge theory and practice. Understanding of current frontier topics (reasoning, multimodal, long-context, alignment) is essential. Code quality matters more than many researchers expect. Labs want researchers who can implement their ideas cleanly.

Strong research postings specify the research area, mention the team you'd join, and describe the problems they're working on. They often list recent publications from the team. Vague 'AI research' postings without specifics usually mean the company wants to sound impressive but doesn't have a real research agenda.

Compensation Benchmarks

Research Scientist roles pay a median of $222,200 based on 197 positions with disclosed compensation. Senior-level AI roles across all categories have a median of $230,000. This role's midpoint ($205K) sits 8% below the category median. Disclosed range: $141K to $268K.

Across all AI roles, the market median is $217,500. Top-quartile compensation starts at $272,100. The 90th percentile reaches $325,000. For comparison, the highest-paying categories include AI Safety ($300,000) and Research Engineer ($280,000). By seniority level: Entry: $120,000; Mid: $200,000; Senior: $230,000; Director: $272,150; VP: $250,000.

AbbVie AI Hiring

AbbVie has 7 open AI roles right now. They're hiring across Research Scientist, AI/ML Engineer, AI Software Engineer. Positions span North Chicago, IL, US, Florham Park, NJ, US. Compensation range: $125K - $393K.

Location Context

AI roles in Chicago pay a median of $205,100 across 97 tracked positions. That's 6% below the national median.

Career Path

Common paths into Research Scientist roles include PhD Student, Research Engineer, Postdoc.

From here, career progression typically leads toward Research Lead, Distinguished Scientist, VP of Research.

The PhD is the entry point for most paths. Choose your advisor and research area carefully since they'll define your first industry position. Publish consistently, contribute to open-source projects in your area, and build relationships at conferences. Industry research offers better compensation and compute resources than academia, but the pressure to show product impact is real.

What to Expect in Interviews

Research interviews are multi-stage: a research talk (present your best paper), technical deep-dives on your methodology, and often a 'research proposal' exercise where you design an experiment to test a hypothesis. Coding rounds test implementation ability alongside theoretical knowledge. Be prepared to implement a paper from scratch and discuss the design choices the authors made. Strong candidates can critique papers constructively and identify gaps in experimental methodology.

When evaluating opportunities: Strong research postings specify the research area, mention the team you'd join, and describe the problems they're working on. They often list recent publications from the team. Vague 'AI research' postings without specifics usually mean the company wants to sound impressive but doesn't have a real research agenda.

AI Hiring Overview

The AI job market has 3,708 open positions tracked in our dataset. By seniority: 102 entry-level, 1,705 mid-level, 1,469 senior, and 432 leadership roles (Director, VP, C-Level). Remote roles make up 14% of the market (508 positions). The remaining 3,180 roles require on-site or hybrid attendance.

The market median for AI roles is $217,500. Top-quartile compensation starts at $272,100. The 90th percentile reaches $325,000. Highest-paying categories: AI Safety ($300,000 median, 21 roles); Research Engineer ($280,000 median, 147 roles); AI Architect ($254,798 median, 67 roles).

Research Scientist roles are concentrated at major AI labs (OpenAI, Anthropic, Google DeepMind, Meta FAIR) and well-funded AI startups. The competition is intense. PhD is effectively required for most positions, and publication track record matters. Compensation is among the highest in AI, reflecting both the scarcity of talent and the strategic importance of research breakthroughs.

The AI Job Market Today

The AI job market spans 3,708 open positions across 16 role categories. The largest categories by volume: AI/ML Engineer (2,605), Data Scientist (310), AI Software Engineer (259). These three account for the majority of open positions, though smaller categories often have higher per-role compensation because of specialized skill requirements.

The seniority mix tells a story about where AI teams are in their maturity. Entry-level roles (102) are outnumbered by mid-level (1,705) and senior (1,469) positions, reflecting that most companies are past the 'build a team from scratch' phase and need experienced engineers who can ship production systems. Leadership roles (Director, VP, C-Level) total 432 positions, representing the bottleneck between technical execution and organizational strategy.

Remote work availability sits at 14% of all AI roles (508 positions), with 3,180 requiring on-site or hybrid attendance. The remote share has stabilized after the post-pandemic correction. Senior and specialized roles (Research Scientist, ML Architect) are more likely to be remote-eligible than entry-level positions, partly because experienced hires have more negotiating power and partly because these roles require less hands-on mentorship.

AI compensation is structured in clear tiers. The market median sits at $217,500. Top-quartile roles start at $272,100, and the 90th percentile reaches $325,000. These figures include base salary with disclosed compensation. Total compensation (including equity, bonuses, and sign-on) runs 20-40% higher at companies that offer those components.

Category matters for compensation. AI Safety roles lead at $300,000 median, while Prompt Engineer roles sit at $140,000. The spread between highest and lowest-paying categories reflects the premium on specialized technical skills versus broader analytical roles.

The most in-demand skills across all AI postings: Python (1,890 postings), Aws (1,103 postings), Azure (877 postings), Rag (855 postings), Gcp (631 postings), Prompt Engineering (560 postings), Pytorch (545 postings), Claude (498 postings). Python dominates, appearing in the vast majority of role descriptions regardless of category. Cloud platform experience (AWS, GCP, Azure) is the second most common requirement. The newer entrants to the top skills list (RAG, vector databases, LLM APIs) reflect the shift from traditional ML toward generative AI applications.

Frequently Asked Questions

Based on 197 roles with disclosed compensation, the median salary for Research Scientist positions is $222,200. Actual compensation varies by seniority, location, and company stage.
PhD strongly preferred for most roles. Deep expertise in a specific area (NLP, computer vision, reinforcement learning, multimodal) is expected. PyTorch is the standard. Publication track record matters. Strong mathematical foundations in linear algebra, probability, optimization, and information theory are assumed.
About 14% of the 3,708 AI roles we track offer remote work. Remote availability varies by company and seniority level, with senior and leadership roles more likely to offer location flexibility.
AbbVie is among the companies actively hiring for AI and ML talent. Check our company profiles for detailed breakdowns of open roles, salary ranges, and hiring trends.
Common next steps from Research Scientist positions include Research Lead, Distinguished Scientist, VP of Research. Progression depends on whether you lean toward technical depth, people management, or product strategy.

Get Weekly AI Career Intelligence

Salary data, skills demand, and market signals from 16,000+ AI job postings. Every Monday.